Search | Result
| ID | 790 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Blood |
| Sample | Blood |
| Disease type | Normal |
| Cell type | T cells |
| Cell type (subtype) | Gamma delta T lymphocytes |
| Cell marker | CD3E, NKG7, TRDC |
| Frequency | |
| PubMed ID | 31118283 |
| Journal | Proc Natl Acad Sci U S A |
| SCI IF | 9.412 |
| Evidence | In the 12k PBMC dataset, n = 862 (7%) PBMC express the CD3E and TRDC but not CD4 and not CD8A genes (red), including n = 375 cells mapped between the cytotoxic CD8 T and NK cell clusters as expected for gammadelta T lymphocytes. Zoom-in of the same cytotoxic cell area of tSNE plot as in Fig. 1, shown with purple color-encoded expression level of NKG7 gene across the NK cells, CD8 T lymphocytes, TCRVdelta1, and TCRVdelta2 gammadelta T lymphocytes. |
| Title | Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of Human TCRVdelta1 and TCRVdelta2 gammadelta T lymphocytes |
| Authors | Gabriele Pizzolato et al. |
| Date | 2019.6 |
| Data available | GSE128223 |
