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ID 7700
Class Mammalia
Species Mouse
Tissue Multiple tissues
Sample Tissue
Disease type NA
Cell type De cluster
Cell type (subtype) Dorsal pancreas
Cell marker Foxa1, Foxa2, Cdh1, Epcam, Pdx1, Mnx1
Frequency
PubMed ID 32855417
Journal Nat Commun
SCI IF 12.121
Evidence Our annotations identified all the major DE organ lineages at E9.5 including:Tbx1+ pharynx, two Nkx2-1/Foxa2+ respiratory clusters (trachea and lung), two Sox2+ esophagus clusters (one of which is likely dorsal based on Mnx1 expression), two Sox2/Osr1+ stomach clusters, two Alb/Prox1/Afp+ hepatic clusters (c1_hepatoblasts and c10_ early hepatocytes with higher Alb/HNF4a expression), Sox17/Pdx1+ ventral hepatopancreatic duct, Mnx1/Pdx1+ dorsal pancreas, and Cdx2+ duodenum
Title Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
Authors Lu Han et al.
Date 2020.8
Data available GSE136689, GSE136687