Search | Result
ID | 7699 |
---|---|
Class | Mammalia |
Species | Mouse |
Tissue | Multiple tissues |
Sample | Tissue |
Disease type | NA |
Cell type | De cluster |
Cell type (subtype) | Ventral hepatopancreatic duct |
Cell marker | Foxa1, Foxa2, Cdh1, Epcam, Pdx1, Sox17 |
Frequency | |
PubMed ID | 32855417 |
Journal | Nat Commun |
SCI IF | 12.121 |
Evidence | Our annotations identified all the major DE organ lineages at E9.5 including:Tbx1+ pharynx, two Nkx2-1/Foxa2+ respiratory clusters (trachea and lung), two Sox2+ esophagus clusters (one of which is likely dorsal based on Mnx1 expression), two Sox2/Osr1+ stomach clusters, two Alb/Prox1/Afp+ hepatic clusters (c1_hepatoblasts and c10_ early hepatocytes with higher Alb/HNF4a expression), Sox17/Pdx1+ ventral hepatopancreatic duct, Mnx1/Pdx1+ dorsal pancreas, and Cdx2+ duodenum |
Title | Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis |
Authors | Lu Han et al. |
Date | 2020.8 |
Data available | GSE136689, GSE136687 |