Search | Result
| ID | 767 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Blood |
| Sample | Cell line |
| Disease type | END(endoderm)-Diff |
| Cell type | Stem cell |
| Cell type (subtype) | Cluster3 |
| Cell marker | NODAL, MIXL1 , LHX1 |
| Frequency | |
| PubMed ID | 30995470 |
| Journal | Cell Rep |
| SCI IF | 9.423 |
| Evidence | MIXL1 is expressed in all clusters except cluster 2;The END annotation in cluster 3 is driven by mesendodermal genes MIXL1, LHX1, and NODAL rather than END hallmarks such as SOX17. |
| Title | Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development |
| Authors | Ryan M.J. Genga et al. |
| Date | 2019.4 |
| Data available | GSE127202 |
