Search | Result

ID 7659
Class Mammalia
Species Mouse
Tissue Melanoma
Sample Tissue
Disease type Melanoma
Cell type Neural cells
Cell type (subtype) Neural crest cells
Cell marker Ngfr, Nestin, Tubb3
Frequency
PubMed ID 31685822
Journal Nat Commun
SCI IF 12.121
Evidence Overall, all 4 melanoma clusters showed reduced expression of melanocytic markers like Dct, MITF and Pmel, along with elevated expression of melanoma markers (S100b, MCAM and Sox10) and neuronal and neural crest markers (Nestin, Tubb5 and Ngfr)
Title A novel Mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling Human disease.
Authors Qi Sun, Wendy Lee. et al.
Date 2019.11
Data available GSE113502