| Evidence |
As expected, the majority of the cells were of neural crest origin, accounting for over 9000 of the 10, 586 cells and are distributed in two subgroups, NC1 and NC2, representing cells in the proximal (expressing Barx1) and distal (expressing Hand2) regions of the E10.5 mandibular arch, respectively. About 8% of the cells were epithelial cells, which are marked by expression of Epcam (830 cells, including both endoderm and ectoderm cells). The endothelial cells (234 cells, marked by Pecam1 expression) and other mesoderm-derived cells (249 cells) were also grouped according to their cell type identity |
