Search | Result
| ID | 7507 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Lung |
| Sample | Cell line |
| Disease type | Allergic asthma |
| Cell type | Neutrophils |
| Cell type (subtype) | Neutrophils |
| Cell marker | S100a8, S100a9, Csf3r, CD45 |
| Frequency | |
| PubMed ID | 31591573 |
| Journal | Nat Immunol |
| SCI IF | 20.479 |
| Evidence | To investigate the transcriptional diversity of lung neutrophils, we performed scRNA-seq. Twenty-four hours after vehicle, LPSlo and LPShi i.n., neutrophils were first enriched from lung single-cell suspensions pooled from 3 BALB/c Mouse per condition by negative selection with MACS and were then FACS sorted as CD45+ cells (Supplementary Fig. 2a_c). |
| Title | Locally instructed CXCR4 neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps. |
| Authors | Radermecker C et al. |
| Date | 2019.11 |
| Data available | NA |
