Search | Result
| ID | 7497 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Lung |
| Sample | Tissue |
| Disease type | Influenza A virus (IAV) infection |
| Cell type | Granulocytes |
| Cell type (subtype) | C13 granulocytes |
| Cell marker | Ccl3, Il1a, Il1b, Ccl4, Cxcl10 |
| Frequency | |
| PubMed ID | 32101596 |
| Journal | PLoS Pathog |
| SCI IF | 6.218 |
| Evidence | (S2A Fig);The isolated PD-L1+ neutrophils (PD-L1+CD11b+Ly6G+) at day 2 p.i. harbored much higher viral RNA and IL-1alpha mRNA levels, as well as higher Ccl3, Ccl4, IL-1beta mRNA levels, compared with PD-L1- neutrophils (PD-L1-CD11b+Ly6G+), indicating that the C13 PD-L1+ neutrophils generated high pro-inflammatory cytokine mRNA level in the lung at early stage of IAV infection (Fig 2H and S15A Fig). |
| Title | Two waves of pro-inflammatory factors are released during the influenza A virus (IAV)- driven pulmonary immunopathogenesis |
| Authors | Junsong Zhang et al. |
| Date | 2020.2 |
| Data available | NA |
