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ID 6562
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type Abdominal aortic aneurysm
Cell type Macrophages
Cell type (subtype) Macrophages
Cell marker Adgre1, Cd68, Cd11b
Frequency
PubMed ID 30479344
Journal Nat Commun
SCI IF 12.121
Evidence ~83% of the cells that expressed Ntn1 were macrophages (Cd11b+/Cd68+/Adgre1+) while only ~7% of T cells (Cd3e+), ~5% of B cells (Cd19+), ~0.5% of neutrophils (Ly6g+), and ~3% of dendritic cells (Itgax+) were detected as Ntn1 positive
Title Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
Authors Tarik Hadi et al.
Date 2018.11
Data available GSE118237