Search | Result
ID | 7205 |
---|---|
Class | Mammalia |
Species | Mouse |
Tissue | Liver |
Sample | Tissue |
Disease type | liver regeneration |
Cell type | Progenitor cells |
Cell type (subtype) | Bipotent liver progenitors |
Cell marker | Gata6, Yap |
Frequency | |
PubMed ID | 33208554 |
Journal | JCI Insight |
SCI IF | 6.205 |
Evidence | The number of cells expressing genes that promote adult hepatocyte dedifferentiation intobipotent liver progenitors (Yap, Gata6) (7, 8) and mark hepatocyte precursors (AFP) (9) or immature cholangiocytes (e.g., Sox9, Hnf1b) (10, 11) also increased (Supplemental Figure 3F). |
Title | Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration |
Authors | Tianyi Chen et al. |
Date | 2020.11 |
Data available | GSE158866 [scRNA-Seq], and GSE158873 [scATAC-Seq] |