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ID 7281
Class Mammalia
Species Mouse
Tissue Liver
Sample Tissue
Disease type NASH
Cell type Macrophages
Cell type (subtype) Macrophages
Cell marker Csf1r
Frequency
PubMed ID 31398325
Journal Mol Cell
SCI IF 15.584
Evidence Endothelial cellss, macrophages, T cells, B cells, cholangiocytes, plasma B cells, dendritic cells (DCs), HSCs, hepatocytes, , Fig1E;This cluster can be further divided into two groups of cells representing KCs and monocyte-derived macrophages (MDMs) based on their marker gene expression profile (Figure 4B). KCs were char_x0002_acterized by high expression of Adgre1 (encoding F4/80) and Clec4f, whereas MDMs exhibited high expression of Itgam (Cd11b) and Ccr2, a chemokine receptor important for infiltration of circulating monocytes
Title Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis
Authors Xuelian Xiong et al.
Date 2019.8
Data available GSE129516