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ID 7200
Class Mammalia
Species Mouse
Tissue Liver
Sample Organoids
Disease type Liver Fibrosis
Cell type Stellate cell
Cell type (subtype) Resting hepatic stellate cell
Cell marker Fcna, Angptl6, Fgf21
Frequency
PubMed ID 31137713
Journal MDPI cells
SCI IF 4.829
Evidence resting HSCs were uniquely characterized by a high expression of ficolin A (Fcna), which has been described to trim extracellular collagen as well as being an activator of a lectin complement pathway, and the hepatokine (Angptl6), an inducer of energy expenditure and regulator of the expression of fibroblast derived growth factor 21 (Fgf21) in white adipose tissue
Title Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis
Authors Oliver Krenkel et al.
Date 2019.5
Data available NA