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ID 7180
Class Mammalia
Species Mouse
Tissue Liver
Sample Organoids
Disease type Necrotic hepatitis, nonalcoholic steatohepatitis
Cell type Erythrophagocytosis
Cell type (subtype) Erythrophagocytosis
Cell marker Hba-a1, Marco
Frequency
PubMed ID 32663195
Journal J Clin Invest
SCI IF 11.864
Evidence This population was also positive for Marco expression coinciding with the erythrophagocytosis marker Hba-a1 (double-positive in Figure 2F). In addition, a strong signal for the previously identified marker gene for erythrophagocytes, Marco, and for the gene expressing the heme-inducible transcription factor, Spic, was observed.
Title Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes
Authors Marc Pfefferlé et al.
Date 2020.1
Data available GSE145244