| Evidence |
Figure 1 / FIgure 3 / We identified Adamtsl2 and Ngfr as the best candidate markers. Using a combination of a highly sensitive modified in situ RNA hybridization procedure (RNAscope) and immunofluorescence staining, we confirmed Adamtsl2 and NGFR to be mesenchymal markers each labeling a subpopulation of HSCs (Figure S4A). /Table S1. Marker and Zonation Genes, Related to Figures 1, 2, 3, 4, and 5. This table provides the list of marker genes specific to each of the identified clusters in the homeostatic murine hepatic mesenchyme dataset (Figure 1B), the homeostatic murine hepatic mesenchyme SmartSeq2 dataset (Figure S3A), and the homeostatic and fibrotic murine hepatic mesenchyme dataset (Figure 3A). It also provides the list of genes used as zonation signatures for analysis (Figures 2A, 4A, and S8F). |
