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ID 6776
Class Mammalia
Species Mouse
Tissue Hippocampus
Sample Tissue
Disease type brain
Cell type Neural cells
Cell type (subtype) Trilaminar cells
Cell marker Gad1, Sst, Pvalb, Ntng1, Slc32a10, Chrm2
Frequency
PubMed ID 29912866
Journal PLoS Biol
SCI IF 7.706
Evidence Continent 6 was identified with Sst-negative long-range projection interneurons. It divided into two distinct clusters, both of which were strongly positive for Ntng1. The first stronglyexpressed Chrm2 but lacked Sst and Pvalb, identifying them as trilaminar cells. The second subgroup lacked most classical molecular markers; this fact, together with their inferred laminar location at the stratum radiatum / stratum lacunosum moleculare (sr/slm) border, identified them as putative radiatum-retrohippocampal neurons that project to the retrosplenial cortex.
Title Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics
Authors Kenneth D Harris et al.
Date 2018.6
Data available GSE99897