Search | Result
| ID | 6934 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Islets |
| Sample | Tissue |
| Disease type | Type 1 Diabetes |
| Cell type | Beta cells |
| Cell type (subtype) | Beta cells |
| Cell marker | Ins1, Ins2 |
| Frequency | |
| PubMed ID | 30799288 |
| Journal | Cell Metab |
| SCI IF | 21.567 |
| Evidence | To identify the beta cell subpopulation we first clustered the resulting 32563 x 27633 matrix using the recipe according to Zheng et al. (2017) implemented in SCANpy version 4.4.0 (Wolf et al., 2018) with the default parametersand validated our selection by thresholding the (strongly bi-modal) distribution of the total Ins1 and Ins2 expression per cell. This resulted in 4002 beta cells, which we further processed independently. |
| Title | Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes |
| Authors | Peter J. Thompson et al. |
| Date | 2019.2 |
| Data available | GSE117770 |
