Search | Result
| ID | 6933 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Islets |
| Sample | Tissue |
| Disease type | Degradation |
| Cell type | Pracreatic beta cells |
| Cell type (subtype) | Pracreatic beta cells |
| Cell marker | MafA, Ucn3, Glut2, Ins1, Ins2 |
| Frequency | |
| PubMed ID | 32182217 |
| Journal | J Clin Invest |
| SCI IF | 11.864 |
| Evidence | the endocrine progenitor cell marker Ngn3 was among the top upregulated genes, while beta cell_specific maturation markers, such as MafA (39), Ucn3 (40), Glut2, Ins1, and Ins2, were among the top downregulated genes |
| Title | Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-beta signaling |
| Authors | Haibo Xu et al. |
| Date | 2020.9 |
| Data available | GSE137785 |
