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ID 6932
Class Mammalia
Species Mouse
Tissue Islets
Sample Tissue
Disease type Type 1 diabetes
Cell type Pancreatic cell
Cell type (subtype) Pancreatic delta cells
Cell marker Hhex, Rbp4
Frequency
PubMed ID 32220307
Journal Cell Metab
SCI IF 21.567
Evidence To investigate whether the changes in the characteristics of b cellswere only restricted to the hormone genes, we examined theexpression of the canonical a cell (Irx2, Ttr) (Petri et al., 2006; Su et al., 2012) and d cell markers (Hhex, Rbp4) (Artner et al., 2010; Zhang et al., 2014) within the b cell clusters
Title Beta Cell Dedifferentiation Induced by IRE1alpha Deletion Prevents Type 1 Diabetes
Authors Hugo Lee et al.
Date 2020.4
Data available GSE144471