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ID 6903
Class Mammalia
Species Mouse
Tissue Intestine
Sample Tissue
Disease type Atypical teratoid/rhabdoid tumors
Cell type Macrophages
Cell type (subtype) Macrophages
Cell marker Cd68, Ms4a7, Cd74, Tgfbi, H2-Aa
Frequency
PubMed ID 31848709
Journal Acta Neuropathol
SCI IF 14.251
Evidence By using MG-specifc markers (e.g., P2ry12, Fig. 3b) and MAC-specifc markers (e.g., Ms4a7, Fig. 3c), we further classifed cluster 4 cells as MG, and clusters 3, 7 and 17 as MACs.Fig.3f. This exchange of genetic information was further underlined by other markers, like Cd68 as MAC-specific marker and Cd44, which was already found to be involved in tumor cell fusion with MACs in glioblastoma.
Title Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance
Authors Viktoria Melcher et al.
Date 2019.12
Data available GSE141534