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ID 6879
Class Mammalia
Species Mouse
Tissue Intestine
Sample Tissue
Disease type Mouse Model
Cell type Crypt cells
Cell type (subtype) Crypt cells
Cell marker Ly6a
Frequency
PubMed ID 29950724
Journal Nature
SCI IF 49.962
Evidence One of the most highly upregulated genes was Ly6a, which encodes Sca-1, a surface protein that is associated with proliferative cells but is not present in Humans. Therefore, Sca-1 was a useful marker of crypt cells responding to H. polygyrus-driven epithelial disruption.
Title Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
Authors Nusse et al.
Date 2018.7
Data available NA