Search | Result
ID | 6879 |
---|---|
Class | Mammalia |
Species | Mouse |
Tissue | Intestine |
Sample | Tissue |
Disease type | Mouse Model |
Cell type | Crypt cells |
Cell type (subtype) | Crypt cells |
Cell marker | Ly6a |
Frequency | |
PubMed ID | 29950724 |
Journal | Nature |
SCI IF | 49.962 |
Evidence | One of the most highly upregulated genes was Ly6a, which encodes Sca-1, a surface protein that is associated with proliferative cells but is not present in Humans. Therefore, Sca-1 was a useful marker of crypt cells responding to H. polygyrus-driven epithelial disruption. |
Title | Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche |
Authors | Nusse et al. |
Date | 2018.7 |
Data available | NA |