Evidence |
our results identified monocyte (Cd14, Fcgr3), macrophage (Adgre1, Csf1r), dendritic cell (Flt3), T cell (Cd3g, Cd4, Cd8b1) and natural killer cell (Ncr1), B cell (Cd19, Cd79a, Jchain) and plasma cell (Jchain, Sdc1), Endothelial cells (Pecam1, Cdh5), and mesenchymal stromal/stem cell (MSC, expressing Lum, Dcn, Cd34, Pdgfra) (Online Figure III).In addition, we also identified two other T cell populations enriched in the allografts, including a resting T cell population lacking expression of cytokines, which was annotated as na_ve T cells (cluster 4, expressing Ccr7 and Sell, but low levels of Cd44), and a population of Th17 cell (cluster 9, expressing Rorc, Rora, Ltb4r1, Il17a and Tnf, Figure 3F) |