Search | Result
| ID | 6941 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Islets |
| Sample | Tissue |
| Disease type | Type 1 diabetes |
| Cell type | Islet cells |
| Cell type (subtype) | Islet alpha cells |
| Cell marker | Ttr, Irx2 |
| Frequency | |
| PubMed ID | 32220307 |
| Journal | Cell Metab |
| SCI IF | 21.567 |
| Evidence | To investigate whether the changes in the characteristics of b cellswere only restricted to the hormone genes, we examined theexpression of the canonical a cell (Irx2, Ttr) (Petri et al., 2006; Su et al., 2012) and d cell markers (Hhex, Rbp4) (Artner et al., 2010; Zhang et al., 2014) within the b cell clusters |
| Title | Beta Cell Dedifferentiation Induced by IRE1alpha Deletion Prevents Type 1 Diabetes |
| Authors | Hugo Lee et al. |
| Date | 2020.4 |
| Data available | GSE144471 |
