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ID 7042
Class Mammalia
Species Mouse
Tissue Kidney
Sample Organoids
Disease type UA crystal
Cell type Macrophages
Cell type (subtype) M2-like macrophages
Cell marker Adgre1, Ptprc, Mertk, Stab1
Frequency
PubMed ID 32938648
Journal J Am Soc Nephrol
SCI IF 9.274
Evidence In addition, we used common genes from the literature to identify inflammatory signaling pathways such as JAK/STAT (Figure 6D), and different immune cell subsets57, 58 including proinflammatory M1-like (Figure 6E) and alternatively activated M2-like macrophages (Figure 6F), neutrophils (Figure 6G), and conventional dendritic cell (cDC) subsets (Figure 6, Hand I).
Title Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease
Authors Markus Sellmayr et al.
Date 2020.12
Data available NA