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ID 6718
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type Transplant arteriosclerosis
Cell type Stromal cells
Cell type (subtype) Mesenchymal stem_stromal cells
Cell marker Dcn, Pdgfra, Lum, Cd34, Ly6a
Frequency
PubMed ID 32689904
Journal Circ Res
SCI IF 14.467
Evidence our results identified monocyte (Cd14, Fcgr3), macrophage (Adgre1, Csf1r), dendritic cell (Flt3), T cell (Cd3g, Cd4, Cd8b1) and natural killer cell (Ncr1), B cell (Cd19, Cd79a, Jchain) and plasma cell (Jchain, Sdc1), Endothelial cells (Pecam1, Cdh5), and mesenchymal stromal/stem cell (MSC, expressing Lum, Dcn, Cd34, Pdgfra) (Online Figure III).Cluster 1 and 2 expressed high levels of canonical stem cell surface markers (Ly6a, Cd34, Pdgfra), as well as mesenchymal markers (Lum, Dcn), suggestive of mesenchymal stromal cells, which is important in tissue repair and regeneration
Title Impact of Local Allo-Immunity and Recipient Cells in Transplant Arteriosclerosis
Authors Jingjing Cai et al.
Date 2020.9
Data available GSE149452, GSE140812 and GSE140968