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ID 6569
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type coronary artery disease
Cell type Macrophages
Cell type (subtype) Macrophages
Cell marker Lgals3
Frequency
PubMed ID 31359001
Journal Nat Med
SCI IF 36.13
Evidence Phenotypically modulated SMCs have previously been noted to express markers associated with myofibroblasts (Acta2), mesenchymal stem cells (Sca1) and macrophages (Lgals3) 6 , and this information was employed to suggest evidence of transdifferentiation into these cellular lineages.
Title Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Authors Robert C Wirka et al.
Date 2019.8
Data available GSE131778