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ID 6485
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type athero-prone aortic arch (AA) and the more disease-resistant descending thoracic aorta (DT)
Cell type Muscle cells
Cell type (subtype) DT region
Cell marker Acta2, Myh11, Tagln, Hoxa7
Frequency
PubMed ID 30385745
Journal Nat Commun
SCI IF 12.121
Evidence Consistent with the region-specific gene signatures identified by bulk expression analysis, genes such as Pde1c and Hand2 were almost exclusively detected in cells from the AA region and Hoxa7 in cells from the DT region
Title Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy Mouse vessels
Authors Lina Dobnikar et al.
Date 2018.12
Data available GSE79436, GSE117963