ID |
6485 |
Class |
Mammalia |
Species |
Mouse |
Tissue |
Heart |
Sample |
Tissue |
Disease type |
athero-prone aortic arch (AA) and the more disease-resistant descending thoracic aorta (DT) |
Cell type |
Muscle cells |
Cell type (subtype) |
DT region |
Cell marker |
Acta2, Myh11, Tagln, Hoxa7 |
Frequency |
|
PubMed ID |
30385745
|
Journal |
Nat Commun |
SCI IF |
12.121 |
Evidence |
Consistent with the region-specific gene signatures identified by bulk expression analysis, genes such as Pde1c and Hand2 were almost exclusively detected in cells from the AA region and Hoxa7 in cells from the DT region |
Title |
Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy Mouse vessels |
Authors |
Lina Dobnikar et al. |
Date |
2018.12 |
Data available |
GSE79436, GSE117963 |