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ID 6479
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type Normal
Cell type Endothelial cells
Cell type (subtype) Vascular endothelial cells
Cell marker Cdh5, Fabp4, Cav1
Frequency
PubMed ID 30283141
Journal Nature
SCI IF 49.962
Evidence From the cardiac and aortic tissue of 3 female and 2 male Mouse, 624 single cells were profiled with the microfluidic droplet platform and grouped into 5 clusters vascular endothelial cells (Fabp4+, Cdh5+, Cav1+)1 , fibroblasts (Ddr2+ , Tcf21+ , Col3a1+ , Col1a2+ , Col1a1+)2 , atrial cardiomyocytes (Nppa+ , Myl7+ , Sln+)1 , endocardial cells (Npr3+ , Pecam1+)3 , immune cells (C1qa+ , H2-Eb1+ ), and myofibroblasts/smooth muscle cells that can be separated by Myh11 and Tcf21 expression.
Title Single-cell transcriptomics of 20 Mouse organs creates a Tabula Muris
Authors Nicholas Schaum et al.
Date 2018.1
Data available GSE109774