| ID |
7786 |
| Class |
Mammalia |
| Species |
Mouse |
| Tissue |
Muscle |
| Sample |
Tissue |
| Disease type |
Duchenne muscular dystrophy |
| Cell type |
Myonuclei |
| Cell type (subtype) |
IIx_b |
| Cell marker |
Ckm, Myh1, Myh4, Tnnc2, Tnni2, Mb, Cox6a2, Cox6c, Atp5e, Atp5g1 |
| Frequency |
|
| PubMed ID |
33148801
|
| Journal |
Proc Natl Acad Sci U S A |
| SCI IF |
9.412 |
| Evidence |
Cluster IIx_b, which highly expresses both Myh1 and Myh4 transcripts, displayed high levels of the transcripts of fast isoforms of troponins (Tnnc2 and Tnni2), myoglobin (Mb), enzymes of cytochrome C oxidase (Cox6a2 and Cox6c), and adenosine 5′-triphosphate synthase complexes (Atp5e and Atp5g1) (SI Appendix, Fig. S4C and Dataset S3). |
| Title |
Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing |
| Authors |
Francesco Chemello et al. |
| Date |
2020.11 |
| Data available |
GSE156498 |
