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ID 6438
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type Normal
Cell type Cardiomyocytes
Cell type (subtype) Cardiomyocytes
Cell marker Tnni3
Frequency
PubMed ID 30283141
Journal Nature
SCI IF 49.962
Evidence FACS sorted cardiac cells and picked cardiomyocytes formed 12 clusters totaling 4, 365 cells. We observe cardiomyocytes (Tnni3+ ), vascular Endothelial cellss (Cdh5+ , Pecam1+ , Fabp4+ , Cav1+ ), aortic Endothelial cellss (Ehd3+ ), endocardial cells (Npr3+ ), fibroblasts (Dcn+ , Gsn+ ), smooth muscle cells (Myh11+ ), and 2 clusters of immune cells (C1qa+ ). We also tracked the chamber of origin for all cells, with cells from each chamber present in all clusters.
Title Single-cell transcriptomics of 20 Mouse organs creates a Tabula Muris
Authors Nicholas Schaum et al.
Date 2018.1
Data available GSE109774