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ID 6426
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type Atherosclerosis
Cell type Macrophages
Cell type (subtype) TREM2hi macrophages
Cell marker Trem2, Cd9, Spp1, Ctsb, Ctsd, Hvcn1, Ctsz
Frequency
PubMed ID 29545365
Journal Circ Res
SCI IF 14.467
Evidence Besides Trem2, TREM2hi macrophages displayed a unique gene signature with expression of, for example, Cd9, Spp1 (encoding osteopontin), Hvcn1, and several cathepsins (Ctsd, Ctsb, and Ctsz; Figure 2B and 2C; Online Table IV).
Title Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis
Authors Clement Cochain et al.
Date 2018.4
Data available GSE97310