Search | Result
| ID | 5745 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Colon |
| Sample | Tissue |
| Disease type | Normal |
| Cell type | Epithelial cells |
| Cell type (subtype) | Intestinal epithelial stem cells and transit-amplifying cells |
| Cell marker | Epcam, Krt19, Mki67, Lgr5, Axin2 |
| Frequency | |
| PubMed ID | 33306673 |
| Journal | Plos Biol |
| SCI IF | 7.076 |
| Evidence | three major groups:Epithelium (Epcam+, Krt19+), stroma (Vim+, Col1a1+), and endothe- lium (Pecam1+) . Clusters 11 and 5 represent IESC and transit-amplifying cells (TA), respectively, based on the expression of Lgr5, Axin2, and Mki67 (Fig 1D) in combination with their high proliferative activity |
| Title | Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis |
| Authors | Michael David Bru _ gger et al. |
| Date | 2020.11 |
| Data available | GSE151257 |
