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ID 7442
Class Mammalia
Species Mouse
Tissue Lung
Sample Organoids
Disease type ST2-deficient
Cell type Macrophages
Cell type (subtype) Alternatively activated macrophages
Cell marker Arg1, Itgax, Retnla, Chil3, Cd206
Frequency
PubMed ID 32963227
Journal Nat Commun
SCI IF 12.121
Evidence Lung resident macro phages express CD206, a marker of AAMs and are thought tooriginate from three distinct precursors. In addition, increased mRNA expression of the AAM markers, Itgax, Cd206, Retnla, Arg1, and Chil3 was observed in total BALcells isolated from NA-treated Mouse, when compared to na_ve(Supplementary Fig. 1f).
Title IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration
Authors Rania Dagher et al.
Date 2020.9
Data available GSE155261