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ID 603
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type Normal
Cell type CD4 T cells
Cell type (subtype) CD4-CTL cells cluster 3 and 4
Cell marker IL7R, LTB, CD28, JUNB, CD27, CD12
Frequency
PubMed ID 29352091
Journal Sci Immunol
SCI IF 13.44
Evidence those in clusters 3 and 4 expressed lower levels of KLRG1 transcripts and higher levels of transcripts encoding IL-7R (IL7R or CD12), Transcripts encoding CD27 and CD28 costimulation molecules, lymphotoxin (LTB), and JUNB TF were also expressed at higher levels in clusters 3 and 4
Title Precursors of Human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis
Authors Patil VS, et al
Date 2018
Data available GSE106544.