Search | Result
ID | 602 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Blood |
Sample | Blood |
Disease type | Normal |
Cell type | CD4 T cells |
Cell type (subtype) | CD4-CTL cells cluster 1 and 2 |
Cell marker | ZNF683, KLRG1, CX3CR1, PRSS23, SPON2, TCF7 , CRTAM |
Frequency | |
PubMed ID | 29352091 |
Journal | Sci Immunol |
SCI IF | 13.44 |
Evidence | Cells in clusters 1 and 2 expressed higher levels of KLRG1 , and CX3CR1 (7, 43) transcripts. Genes linked to cell survival and CD4-CTL function such as PRSS23, SPON2, TCF7 (encodes for TCF1), CRTAM, and ZNF683 (encodes for Hobit) (24, 46_51) were also highly expressed in single cells from clusters 1 and 2 |
Title | Precursors of Human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis |
Authors | Patil VS, et al |
Date | 2018 |
Data available | GSE106544. |