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ID 602
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type Normal
Cell type CD4 T cells
Cell type (subtype) CD4-CTL cells cluster 1 and 2
Cell marker ZNF683, KLRG1, CX3CR1, PRSS23, SPON2, TCF7 , CRTAM
Frequency
PubMed ID 29352091
Journal Sci Immunol
SCI IF 13.44
Evidence Cells in clusters 1 and 2 expressed higher levels of KLRG1 , and CX3CR1 (7, 43) transcripts. Genes linked to cell survival and CD4-CTL function such as PRSS23, SPON2, TCF7 (encodes for TCF1), CRTAM, and ZNF683 (encodes for Hobit) (24, 46_51) were also highly expressed in single cells from clusters 1 and 2
Title Precursors of Human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis
Authors Patil VS, et al
Date 2018
Data available GSE106544.