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ID 6011
Class Mammalia
Species Mouse
Tissue Epiblast stem cells
Sample Cell line
Disease type Normal
Cell type Pluripotent cells
Cell type (subtype) Pluripotent cells
Cell marker Zfp42, Nanog, Pou5f1, Esrrb, Dppa3, Tcf15, Cbx7
Frequency
PubMed ID 30118958
Journal Stem Cell Res
SCI IF 4.789
Evidence Visualization of the expression of a marker genes for pluripotent cells (Zfp42), epiblast stem cells(Fgf5), neuroectoderm (Sox1), and primitive streak (T). We first examined the expression of pluripotency marker genes, including Nanog, Pou5f1, and Esrrb, and confirmed that there was a gradual decrease, but not a complete loss of expression of genes from day 0 to day 6. Clusters D4_G5 and D4_G6 were characterized by high levels of pluripotency genes such as Zfp42, Dppa3, Tcf15, and Cbx7, the ESC-specific Polycomb repressive complex 1 (PRC1) member
Title A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo
Authors Abby Spangler et al.
Date 2018.8
Data available GSE100597