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ID 5925
Class Mammalia
Species Mouse
Tissue Embryos
Sample Tissue
Disease type Mammalian lip and primary palate
Cell type Ectoderm cells
Cell type (subtype) Surface.2
Cell marker Epcam, Igfbp5, Pdgfa, Sfn, Spint2, Cre, LacZ, Wnt3, Robo2, Pcp4, Pcp1
Frequency
PubMed ID 31118233
Journal Development
SCI IF 5.611
Evidence Finally, the cluster designated as ectoderm _ based on expression of pan-ectoderm markers such as Epcam, Igfbp5 and Pdgfa _ was confirmed to be ectoderm derived as it also expressed significant levels of transcripts corresponding to Cre recombinase and/or LacZ (Fig. S2E).Igfbp5, Sfn and Spint2 are markers for ectoderm.The expression of Cre and LacZ confirm the lineage of the ectodermal cells. Fig. 5. Reclustering identifies specific ectodermal cell populations.
Title The molecular anatomy of mammalian upper lip and primary palate fusion at single cell resolution
Authors Hong Li et al.
Date 2019.6
Data available GSE132462