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ID 569
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type SARS-CoV-2
Cell type T cells
Cell type (subtype) T follicular-helper-like
Cell marker IL21 , POU2AF1
Frequency
PubMed ID 33296686
Journal Immunity
SCI IF 31.745
Evidence These were assigned as T follicular-helper-like (Tfh-like, key marker genes IL21 , POU2AF1 ), transitional memory ( CD28, IL7R ), central memory ( CCR7, SELL ), cytotoxic ( IFNG, CSF2, PRF1, GNLY ), type-I interferon response ( MX1, OAS1 ) and cycling T cells ( MKI67, CDK1 )
Title Low-Avidity CD4 + T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19
Authors Petra Bacher et al.
Date 2020.12
Data available GSE162086