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ID 568
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type NA
Cell type T cells
Cell type (subtype) T effec or memory cells
Cell marker CD3, CD4, CD8
Frequency
PubMed ID 30890702
Journal Nat Commun
SCI IF 12.121
Evidence thymic emigrant and naive subsets of CD3+CD4+ T cells. The most notable overall changes in the TET2 mutation carriers were the high percentages of activated (CD38lowCD21low) CD19+ Bcells and low percentages of CD3+CD4/8+CCR7 -CD45RA- T effector memory cells.
Title Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in Humans
Authors Eevi Kaasinen et al.
Date 2019
Data available NA