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ID 5616
Class Mammalia
Species Mouse
Tissue Breast
Sample Tissue
Disease type triple-negative breast cancer
Cell type T cells
Cell type (subtype) Cytotoxic T cells
Cell marker Pdcd1, Ctla4, Eomes, Lag3, Tim3
Frequency
PubMed ID 31730857
Journal Cell
SCI IF 38.637
Evidence Among cells with cytotoxic gene expression profiles, cells with high expression of checkpoint and exhaustion markers Eomes, Pdcd1, Ctla4, Lag3, and Tim3 were frequent
Title B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
Authors Daniel P. Hollern et al.
Date 2020.11
Data available GSE136207