Search | Result
| ID | 5554 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Brain |
| Sample | Organoids |
| Disease type | Obesity |
| Cell type | Neural cells |
| Cell type (subtype) | Mediobasal hypothalamic agouti related peptide-expressing neurons |
| Cell marker | Agrp |
| Frequency | |
| PubMed ID | 32955435 |
| Journal | eLife |
| SCI IF | 7.077 |
| Evidence | First, to validate that our ES approach was able to delineate cell type-specific genes, we, for each of the four ES metrics, computed_Sw_stimates across four cell types with genes known to be specifically expressed in these cell types, namely hepatocytes (Apoa2), pancreatic alpha-cells (Gcg), striatum medium spiny neurons (Drd2) and mediobasal hypothalamic agouti related peptide (Agrp)-expressing neurons (Agrp). |
| Title | Genetic mapping of etiologic brain cell types for obesity |
| Authors | Pascal N Timshel et al. |
| Date | 2020.9 |
| Data available | GSE74672, GSE87544, GSE113576, GSE93374, GSE125065, GSE109774, SRP135960 |
