| ID |
5479 |
| Class |
Mammalia |
| Species |
Mouse |
| Tissue |
Brain |
| Sample |
Tissue |
| Disease type |
Alzheimer Disease |
| Cell type |
Natural killer (NK) cells |
| Cell type (subtype) |
NK1a |
| Cell marker |
NK1.1, CD45, DX5, Ctsc, Ccl4, Ctsd, Ccl3 |
| Frequency |
|
| PubMed ID |
32503894
|
| Journal |
The Journal of Immunology |
| SCI IF |
4.886 |
| Evidence |
Interestingly, compared with than those in control wildtype mice, NK1a and/or NK1b subsets in 3xTg-AD mice expressed higher amounts of cytotoxic and other effector molecules such Ctsc, Ctsd, Ccl3, and Ccl4, indicating enhanced activity |
| Title |
Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model |
| Authors |
Yuanyue Zhang et al. |
| Date |
2020.6 |
| Data available |
GSE142853 |
