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ID 5399
Class Mammalia
Species Mouse
Tissue Brain
Sample Tissue
Disease type Healthy
Cell type Neural cells
Cell type (subtype) Inhibitory neurons
Cell marker Gad1, Sst, Npy, Gad2, Tac1, Penk
Frequency
PubMed ID 31932797
Journal Nat Med
SCI IF 36.13
Evidence These clusters were manually identified on the basis of the expression of known cell-type-specific markers (Fig. 1c and Extended Data Fig. 1b) as neurons (Clusters 0, 1, 3, 4, 5), oligodendrocytes (Cluster 2), astrocytes (Cluster 6), microglia (Cluster 7), oligodendrocyte pre_x0002_cursor cells (OPCs, Cluster 8) and Endothelial cellss (Cluster 9) (Fig. 1d).
Title Human and Mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer disease.
Authors Zhou Y et al.
Date 2020.1
Data available GSE140511