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ID 6750
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type Transplant arteriosclerosis
Cell type T cells
Cell type (subtype) T cells
Cell marker Cd4, Cd3g, Cd8b1
Frequency
PubMed ID 32689904
Journal Circ Res
SCI IF 14.467
Evidence our results identified monocyte (Cd14, Fcgr3), macrophage (Adgre1, Csf1r), dendritic cell (Flt3), T cell (Cd3g, Cd4, Cd8b1) and natural killer cell (Ncr1), B cell (Cd19, Cd79a, Jchain) and plasma cell (Jchain, Sdc1), Endothelial cells (Pecam1, Cdh5), and mesenchymal stromal/stem cell (MSC, expressing Lum, Dcn, Cd34, Pdgfra) (Online Figure III).Cluster 7, a CD8+ T cell subset found in both control and allograft group, expressed high levels of cell cycle genes (Birc5, Cks1b, Ube2c) and represented a dividing CD8+ T population
Title Impact of Local Allo-Immunity and Recipient Cells in Transplant Arteriosclerosis
Authors Jingjing Cai et al.
Date 2020.9
Data available GSE149452, GSE140812 and GSE140968