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ID 4282
Class Mammalia
Species Homo sapiens
Tissue Skin
Sample Tissue
Disease type cutaneous squamous cell carcinoma (cSCC)
Cell type Epithelial cells
Cell type (subtype) TSK subpopulation
Cell marker KRT1, KRT5, KRT14, KRT10, VIM, ITGA5
Frequency
PubMed ID 32579974
Journal Cell
SCI IF 38.637
Evidence TSK signature genes were linked to cellular movement and extracellular matrix disassembly, suggesting invasive behavior (Figure 2E). Consistent with this, TSKs expressed classic epithelial-mesenchymal transition (EMT) markers such as VIM and ITGA5 (Figure 2F).
Title Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma
Authors Andrew L Ji et al.
Date 2020.7
Data available GSE144240