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ID 5022
Class Mammalia
Species Mouse
Tissue Bone
Sample Tissue
Disease type Normal
Cell type Hematopoietic cells
Cell type (subtype) Hematopoietic stem and progenitor cells
Cell marker Cd34, Kit
Frequency
PubMed ID 32494068
Journal Nature
SCI IF 49.962
Evidence To validate the cluster order we identified known reciprocal patterns of transcription factor genes (Irf8/Gfi1, Myc/Mxd1 and Cebpa/Cebpe), as well as primary (Elane, Mpo), secondary (Camp, Lcn2, Ltf), and tertiary (Mmp8, Mmp9) granule-protein genes (Fig. 2f) whose expression was significantly correlated to individual clusters (Fig. 2g).
Title Mouse models of neutropenia reveal progenitor-stage-specific defects
Authors David E. Muench et al.
Date 2020.6
Data available GSE120409