Search | Result
ID | 4903 |
---|---|
Class | Mammalia |
Species | Mouse |
Tissue | Blood |
Sample | Blood |
Disease type | chronic viral infection |
Cell type | CD8 T cells |
Cell type (subtype) | CD8 T cells |
Cell marker | NA |
Frequency | |
PubMed ID | 31606264 |
Journal | Immunity |
SCI IF | 31.745 |
Evidence | Cluster 2 was of particular interest given the high co-expression of Pdcd1, Tcf7, Slamf6, and Bcl2 and the relative lack of Gzmb, Havcr2, and markers of the cell cycle. This cluster is reminiscent of recently described TCF-1+ Tex progenitor cells in established exhaustion |
Title | TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision |
Authors | Zeyu Chen et al. |
Date | 2019.1 |
Data available | GSE131535 |