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ID 4843
Class Mammalia
Species Mouse
Tissue Blood
Sample Cell line
Disease type Normal
Cell type Hematopoietic stem cells
Cell type (subtype) Hematopoietic stem cells
Cell marker Fgd5
Frequency
PubMed ID 30561434
Journal eLife
SCI IF 6.677
Evidence Using a transcriptome based screen of more than 40 different hematopoietic cell types, Fgd5 (FYVE, RhoGEF and PH domain containing 5) was identified as a HSC-expressed gene that is rapidly down_x0002_ regulated upon differentiation.
Title Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging
Authors Petter Sa¨wen et al.
Date 2018.12
Data available GSE122473