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ID 8388
Class Mammalia
Species Mouse
Tissue Retina
Sample Organoids
Disease type Spontaneous uveoretinitis
Cell type Macrophages
Cell type (subtype) Macrophage_microglia
Cell marker Trem2, Fcrls, P2ry12, Hexb, Tmem119, Slc2a5, IBA1, Aif1)
Frequency
PubMed ID 31843893
Journal Proc Natl Acad Sci U S A
SCI IF 9.412
Evidence Fig. S3B, Transcripts coding for IBA1 (Aif1), a commonly used marker for microglia and macrophages, were only modestly up-regulated (P value < 0.05 for microglia and P value < 0.01 for mo-MΦs).
Title Comprehensive analysis of a Mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
Authors Jacob S Heng et al.
Date 2019.12
Data available GSE132229, GSM3854512_3854519