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ID 4602
Class Mammalia
Species Homo sapiens
Tissue Tibial articular cartilages
Sample Tissue
Disease type Osteoarthritis
Cell type Immune cells
Cell type (subtype) Proliferating immune cells
Cell marker CCL3, BIRC5, HIST1H4C, BIRC5
Frequency
PubMed ID 32616761
Journal Sci Rep
SCI IF 3.992
Evidence Figure 1d. We also observed four immune subpopulations (clusters 3, 9, 12 and 13) that all expressed PTPRC (CD45) (Supplementary Fig. S1l), and three unique subpopulations, clusters 10, 11 and 14, that expressed specific markers of known cell types, including EC (PLVAP), SMC (ACTA2) and ProIC (HIST1H4C, BIRC5, and CCL3), respectively.
Title Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis
Authors Ching-Heng Chou et al.
Date 2020.7
Data available GSE152805