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ID 4596
Class Mammalia
Species Homo sapiens
Tissue Tibial articular cartilages
Sample Tissue
Disease type Osteoarthritis
Cell type Dendritic cells
Cell type (subtype) Dendritic cells
Cell marker CD1C, FCER1A, HLA-DQA1, HLA-DQA2, OLR1, TLR2
Frequency
PubMed ID 32616761
Journal Sci Rep
SCI IF 3.992
Evidence DC marker genes, FCER1A and CD1C were exclusively expressed in DC. Representative immunofluorescence staining showing co-expression of IL1B and surface biomarkers of I-MΦ and DC, such as HLA-DQA1, HLA-DQA2, OLR1 and TLR2 in Human OA synovium.
Title Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis
Authors Ching-Heng Chou et al.
Date 2020.7
Data available GSE152805