ID |
4596 |
Class |
Mammalia |
Species |
Homo sapiens |
Tissue |
Tibial articular cartilages |
Sample |
Tissue |
Disease type |
Osteoarthritis |
Cell type |
Dendritic cells |
Cell type (subtype) |
Dendritic cells |
Cell marker |
CD1C, FCER1A, HLA-DQA1, HLA-DQA2, OLR1, TLR2 |
Frequency |
|
PubMed ID |
32616761
|
Journal |
Sci Rep |
SCI IF |
3.992 |
Evidence |
DC marker genes, FCER1A and CD1C were exclusively expressed in DC. Representative immunofluorescence staining showing co-expression of IL1B and surface biomarkers of I-MΦ and DC, such as HLA-DQA1, HLA-DQA2, OLR1 and TLR2 in Human OA synovium. |
Title |
Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis |
Authors |
Ching-Heng Chou et al. |
Date |
2020.7 |
Data available |
GSE152805 |