Search | Result
| ID | 4591 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Tibial articular cartilages |
| Sample | Tissue |
| Disease type | Osteoarthritis |
| Cell type | Synoviocytes |
| Cell type (subtype) | Synoviocytes |
| Cell marker | HLA-DQA1, HLA-DQA2, OLR1, TLR2 |
| Frequency | |
| PubMed ID | 32616761 |
| Journal | Sci Rep |
| SCI IF | 3.992 |
| Evidence | Surface markers, HLA-DQA1, HLA-DQA2, OLR1 or TLR2, identified synoviocytes that co-expressed IL-1beta protein and other pro-inflammatory mediators, providing potential identifiers to aid targeting of these pathogenic intra-articular cell subpopulations for depletion or reprogramming. |
| Title | Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis |
| Authors | Ching-Heng Chou et al. |
| Date | 2020.7 |
| Data available | GSE152805 |
